The Acquired Immune System

Acquired TTP: ADAMTS13 meets the immune system.

The majority of the patients affected by acquired thrombotic thrombocytopenic purpura (TTP) develop autoantibodies directed towards ADAMTS13 that interfere with its von Willebrand Factor (VWF) processing activity. B cell responses have been shown to primarily target the spacer domain of ADAMTS13 thereby prohibiting the binding of ADAMTS13 to the VWF A2 domain. In this review we summarize recent...

A Hierarchical Framework of the Acquired Immune System

The acquired immune system provides a general pattern recognition and defence system that modifies itself, adapting to improve its capability with experience. This work elaborates upon and refines the definition of a previously proposed hieratical acquired immune system framework. Rather than trying to fit biological observations in providing a tool for theoretical immunology, the framework is ...

Innate and acquired plasticity of the intestinal immune system.

HAL is a multidisciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L'archive ouverte pluridisciplinaire HAL, est destinée au dépôt età la diffusion de documents scientifiques de niveau r...

The acquired immune system: a vantage from beneath.

Acquired immune deficiency syndrome or acquired immunodeficiency syndrome (AIDS) is a disease of the human immune system cause

Acquired immune deficiency syndrome or acquired immunodeficiency syndrome (AIDS) is a disease of the human immune system caused by the human immunodeficiency virus (HIV). This condition progressively reduces the effectiveness of the immune system and leaves individuals susceptible to opportunistic infections and tumors. HIV is transmitted through direct contact of a mucous membrane or the blood...